Recent trends in next generation immunoinformatics harnessed for universal coronavirus vaccine designReview Published on 2023-03-012023-07-09 Journal: Pathogens and global health [Category] COVID19(2023년), [키워드] characterization database Epitope prediction Human coronavirus immunoinformatics peptide vaccine vaccine target. [DOI] 10.1080/20477724.2022.2072456 PMC 바로가기 [Article Type] Review
An integrated metabolomic and proteomic approach for the identification of covalent inhibitors of the main protease (Mpro) of SARS-COV-2 from crude natural extractsArticle Published on 2023-01-152022-11-15 Journal: Talanta [Category] SARS, 유전자 메커니즘, 치료제, [키워드] Analysis applied approach baicalein binding carried catalytic characteristic Chinese complementary complex Compound Covalent binder Cys145 database drug target electrophilic Final functional HIS163 HIS164 His41 independent inhibitor inhibitors Ion knowledge M pro M(pro) mass mass spectrometry maturation metabolomic metabolomics Michael molecular dynamics MPro nucleophilic peptide platform polyprotein protease protein-ligand Proteins proteomic proteomics residue SARS-CoV-2 SARS-CoV-2. Scutellaria baicalensis tested the SARS-CoV-2 [DOI] 10.1016/j.talanta.2022.123824 PMC 바로가기
A systematic review of the advancement on colorimetric nanobiosensors for SARS-CoV-2 detectionArticle Published on 2023-01-052022-11-15 Journal: Journal of pharmaceutical and biomedical analysis [Category] SARS, 진단, 치료기술, [키워드] addition analyzed applied approach articles biosensors chain Clinical diagnosis coronavirus COVID-19 database Detection limit Diagnosis devices diagnostic diagnostics Direct ELISA enzyme-linked immunosorbent assay faster highlight individual lateral flow immunoassay Masks Nanosensors original form pandemic PCR POC POC. point-of-care reaction researcher SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 viruses Science searched selective severe respiratory syndrome specificity surgical swabs systematic review virus detection Web of Science [DOI] 10.1016/j.jpba.2022.115087 PMC 바로가기
The efficacy and effectiveness of the COVID-19 vaccines in reducing infection, severity, hospitalization, and mortality: a systematic review감염, 중증도, 입원 및 사망률 감소에 대한 COVID-19 백신의 효능 및 효과: 체계적인 검토Article Published on 2022-12-312022-09-11 Journal: Human vaccines & immunotherapeutics [Category] COVID19(2023년), SARS, 변종, [키워드] accelerated approved B.1.1.7 B.1.351 B.1.351 variants COVID-19 COVID-19 pandemic COVID-19 vaccine COVID-19 vaccines database disease transmission effective Effectiveness Efficacy effort growth Hospitalization identify inclusion criteria Infection infections Mortality Pfizer Pfizer/BioNTech populations reduced reducing regimen required Seven severity systematic literature search systematic review Vaccine Vaccine development vaccine. Vaccines variants was performed [DOI] 10.1080/21645515.2022.2027160 PMC 바로가기 [Article Type] Article
Assessing the reporting quality of randomized controlled trials on COVID-19 vaccines: a systematic reviewCOVID-19 백신에 대한 무작위 대조 시험의 보고 품질 평가: 체계적인 검토Article Published on 2022-12-312022-09-11 Journal: Human vaccines & immunotherapeutics [Category] 임상, [키워드] adverse effect Analysis analysis of variance Assessing CONSORT CONSORT statement controlled trials COVID-19 COVID-19 vaccine COVID-19 vaccines criteria current database effective evaluated Evidence groups independent indicate indicated median Mortality no significant difference predicted Randomized Randomized controlled trial Randomized controlled trials RCT RCTs reported Reporting Reporting quality review. Standard systematic review Univariate analysis variance variety [DOI] 10.1080/21645515.2022.2031453 PMC 바로가기 [Article Type] Article
Persistent neuropsychiatric symptoms after COVID-19: a systematic review and meta-analysisReview Article Published on 2022-12-172022-10-27 Journal: Brain Communications [Category] COVID-19, [키워드] 95% confidence interval Anxiety Anxiety Disorder calculated chronic COVID syndrome CINAHL Cognitive impairment conducted consequence control group control groups controls COVID-19 COVID-19 hospitalization COVID-19 infection curated database disorder duration of follow-up Evidence fatigue Follow-up Frequency help heterogeneity Hospitalization indicate Infection Insomnia linear Long COVID management mental health Meta-analysis moderate neurological Neuropsychiatric neuropsychiatry pandemic patients peer-reviewed study persistent post-acute sequelae of COVID-19 post-traumatic Prevalence prevalent Psychological PsycINFO reported symptom searched severity Sleep disturbance Stress Subgroup analysis survivor Symptom Symptoms systematic review unique was measured [DOI] 10.1093/braincomms/fcab297 PMC 바로가기 [Article Type] Review Article
Ontological Analysis of Coronavirus Associated Human Genes at the COVID-19 Disease PortalArticle Published on 2022-12-072023-07-11 Journal: Genes [Category] COVID19(2023년), [키워드] biological knowledgebase COVID-19 database disease enrichment Gene set enrichment liver disease. [DOI] 10.3390/genes13122304 PMC 바로가기
Identification of the Hub Genes and the Signaling Pathways in Human iPSC-Cardiomyocytes Infected by SARS-CoV-2Article Published on 2022-12-012022-11-16 Journal: Biochemical Genetics [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] Analysis applied Bioinformatics analysis biological process Biomarker Brain caused component Cytoscape software database dataset DEGs differentially expressed gene direct infection down-regulated gene enrichment analysis function Gene Expression Omnibus gene expression profile Gene ontology Genes GEO GraphPad Prism software High-throughput sequencing hub genes Human Human iPSC-cardiomyocytes identification infected with SARS-CoV-2 intestine KEGG kidney Kyoto Ligand liver Lung injury mechanisms myocardial injury organ pathway Pathways PPI PPI network protein-protein interaction R software receptor Research respiratory respiratory symptom SARS-CoV-2 SARS-CoV-2. screened sequencing data signaling pathway single-stranded RNA virus statistical analysis statistically significant TNF signaling Type type I interferon up-regulated was obtained was performed website [DOI] 10.1007/s10528-022-10206-7 PMC 바로가기
Effect of colchicine on the outcomes of patients with COVID-19: a systematic review and meta-analysis of randomised controlled trialsCOVID-19 환자의 결과에 대한 콜히친의 영향: 무작위 대조 시험의 체계적인 검토 및 메타 분석Meta-Analysis Published on 2022-12-012022-09-11 Journal: Annals of Medicine [Category] 임상, [키워드] 95% CI addition adverse event adverse events Clinical efficacy clinical outcomes ClinicalTrials Cochrane Library Colchicine control group COVID-19 database diarrhoea Effect higher risk hospital Hospital stay improve clinical outcome mean difference mechanical ventilation Meta-analysis Mortality no significant difference non-invasive ventilation non-invasive ventilation. not reduce Odds ratio outcome OVID Patient patients with COVID-19 Placebo placebos randomised controlled trial RCT RCTs receiving risk SARS-CoV-2 searched significant difference significantly higher standard treatment study group Support systematic review the study group Treatment Web of Science [DOI] 10.1080/07853890.2022.2096919 PMC 바로가기 [Article Type] Meta-Analysis
Severity of SARS-CoV-2 Omicron BA.2 infection in unvaccinated hospitalized children: comparison to influenza and parainfluenza infections예방접종을 받지 않은 입원 소아에서 SARS-CoV-2 Omicron BA.2 감염의 심각도: 인플루엔자 및 파라인플루엔자 감염과의 비교Article Published on 2022-12-012022-09-11 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, [키워드] 95%CI acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adjusted Admission children Clinical outcome coronavirus COVID-19 COVID-19 infection Croup database death had no hospitalisation hospitalisations Hospitalization Hospitalized Infection Influenza Influenza virus initial investigated Mild neurological Neurological complication Neurological complications occurred omicron outcome parainfluenza parainfluenza virus proportion Public Hospital Relative risk required respiratory. retrieved risk SARS-CoV-2 severe acute respiratory syndrome Coronavirus severity uninfected upper airway upper airways vaccination variant viral infections virus viruses were recorded [DOI] 10.1080/22221751.2022.2093135 PMC 바로가기 [Article Type] Article